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Stigmasterol Restores the Balance of Treg/Th17 Cells by Activating the Butyrate-PPARγ Axis in Colitis

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder with gut microbiota disequilibrium and regulatory T (Treg)/T helper 17 (Th17) immune imbalance. Stigmasterol, a plant-derived sterol, has shown anti-inflammatory effects. Our study aimed to identify the effects of stigmasterol on ex...

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Detalles Bibliográficos
Autores principales: Wen, Shuting, He, Long, Zhong, Zhuotai, Zhao, Runyuan, Weng, Senhui, Mi, Hong, Liu, Fengbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526899/
https://www.ncbi.nlm.nih.gov/pubmed/34691046
http://dx.doi.org/10.3389/fimmu.2021.741934