A short-term treatment with BKI-1294 does not protect foetuses from sheep experimentally infected with Neospora caninum tachyzoites during pregnancy

The Neospora caninum Calcium-dependent protein kinase 1 (NcCDPK1) inhibitor BKI-1294 had demonstrated excellent efficacy in a pregnant mouse model of neosporosis, and was also highly efficacious in a pregnant sheep model of toxoplasmosis. In this work, we present the efficacy of BKI-1294 treatment (...

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Detalles Bibliográficos
Autores principales: Sánchez-Sánchez, Roberto, Ferre, Ignacio, Re, Michela, Pérez-Arroyo, Bárbara, Cleofé-Resta, Darío, García, Victor Herrero, Díaz, Manuel Pizarro, Ferrer, Luis Miguel, Ruiz, Hector, Vallejo-García, Raquel, Benavides, Julio, Hulverson, Matthew A., Choi, Ryan, Whitman, Grant R., Hemphill, Andrew, Van Voorhis, Wesley C., Ortega-Mora, Luis Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Regular article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526916/
https://www.ncbi.nlm.nih.gov/pubmed/34655903
http://dx.doi.org/10.1016/j.ijpddr.2021.10.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526916/
https://www.ncbi.nlm.nih.gov/pubmed/34655903
http://dx.doi.org/10.1016/j.ijpddr.2021.10.001

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