Blockade of TLR2 and TLR4 Attenuates Inflammatory Response and Parasite Load in Cutaneous Leishmaniasis

Human cutaneous leishmaniasis (CL) caused by Leishmania braziliensis is characterized by a pronounced inflammatory response associated with ulcer development. Monocytes/macrophages, the main cells harboring parasites, are largely responsible for parasite control. Toll-like receptor (TLR) signaling l...

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Detalles Bibliográficos
Autores principales: Carneiro, Pedro Paulo, Dórea, Andreza S., Oliveira, Walker N., Guimarães, Luiz Henrique, Brodskyn, Claúdia, Carvalho, Edgar M., Bacellar, Olívia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526941/
https://www.ncbi.nlm.nih.gov/pubmed/34691019
http://dx.doi.org/10.3389/fimmu.2021.706510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526941/
https://www.ncbi.nlm.nih.gov/pubmed/34691019
http://dx.doi.org/10.3389/fimmu.2021.706510

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