African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1- and JAK2-mediated signaling

African swine fever virus (ASFV) is a large DNA virus that is highly contagious and pathogenic in domestic pigs with a mortality rate up to 100%. However, how ASFV suppresses JAK-STAT1 signaling to evade the immune response remains unclear. In this study, we found that the ASFV-encoded protein MGF-5...

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Detalles Bibliográficos
Autores principales: Li, Dan, Zhang, Jing, Yang, Wenping, Li, Pan, Ru, Yi, Kang, Weifang, Li, LuLu, Ran, Yong, Zheng, Haixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526981/
https://www.ncbi.nlm.nih.gov/pubmed/34517008
http://dx.doi.org/10.1016/j.jbc.2021.101190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8526981/
https://www.ncbi.nlm.nih.gov/pubmed/34517008
http://dx.doi.org/10.1016/j.jbc.2021.101190

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