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High‐efficiency delivery of CRISPR‐Cas9 by engineered probiotics enables precise microbiome editing

Antibiotic resistance threatens our ability to treat infectious diseases, spurring interest in alternative antimicrobial technologies. The use of bacterial conjugation to deliver CRISPR‐cas systems programmed to precisely eliminate antibiotic‐resistant bacteria represents a promising approach but re...

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Detalles Bibliográficos
Autores principales: Neil, Kevin, Allard, Nancy, Roy, Patricia, Grenier, Frédéric, Menendez, Alfredo, Burrus, Vincent, Rodrigue, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527022/
https://www.ncbi.nlm.nih.gov/pubmed/34665940
http://dx.doi.org/10.15252/msb.202110335