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TIGIT blockade enhances NK cell activity against autologous HIV‐1‐infected CD4(+) T cells

OBJECTIVES: During chronic human immunodeficiency virus (HIV)‐1 infection, inhibitory molecules upregulated on lymphocytes contribute to effector cell dysfunction and immune exhaustion. People living with HIV (PLWH) are at greater risk for age‐related morbidities, an issue magnified by human cytomeg...

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Detalles Bibliográficos
Autores principales: Holder, Kayla A, Burt, Kimberley, Grant, Michael D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527024/
https://www.ncbi.nlm.nih.gov/pubmed/34707863
http://dx.doi.org/10.1002/cti2.1348