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Dual inhibition of TMPRSS2 and Cathepsin Bprevents SARS-CoV-2 infection in iPS cells

It has been reported that many receptors and proteases are required for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. Although angiotensin-converting enzyme 2 (ACE2) is the most important of these receptors, little is known about the contribution of other genes. In this stu...

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Detalles Bibliográficos
Autores principales: Hashimoto, Rina, Sakamoto, Ayaka, Deguchi, Sayaka, Yi, Renxing, Sano, Emi, Hotta, Akitsu, Takahashi, Kazutoshi, Yamanaka, Shinya, Takayama, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527102/
https://www.ncbi.nlm.nih.gov/pubmed/34692233
http://dx.doi.org/10.1016/j.omtn.2021.10.016