Immunosuppressive metabolites in tumoral immune evasion: redundancies, clinical efforts, and pathways forward

Tumors accumulate metabolites that deactivate infiltrating immune cells and polarize them toward anti-inflammatory phenotypes. We provide a comprehensive review of the complex networks orchestrated by several of the most potent immunosuppressive metabolites, highlighting the impact of adenosine, kyn...

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Detalles Bibliográficos
Autores principales: Jennings, Maria Rain, Munn, David, Blazeck, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527165/
https://www.ncbi.nlm.nih.gov/pubmed/34667078
http://dx.doi.org/10.1136/jitc-2021-003013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527165/
https://www.ncbi.nlm.nih.gov/pubmed/34667078
http://dx.doi.org/10.1136/jitc-2021-003013

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