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Immunosuppressive metabolites in tumoral immune evasion: redundancies, clinical efforts, and pathways forward
Tumors accumulate metabolites that deactivate infiltrating immune cells and polarize them toward anti-inflammatory phenotypes. We provide a comprehensive review of the complex networks orchestrated by several of the most potent immunosuppressive metabolites, highlighting the impact of adenosine, kyn...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BMJ Publishing Group
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527165/ https://www.ncbi.nlm.nih.gov/pubmed/34667078 http://dx.doi.org/10.1136/jitc-2021-003013 |