Depletion of T cells via Inducible Caspase 9 Increases Safety of Adoptive T-Cell Therapy Against Chronic Hepatitis B

T-cell therapy with T cells that are re-directed to hepatitis B virus (HBV)-infected cells by virus-specific receptors is a promising therapeutic approach for treatment of chronic hepatitis B and HBV-associated cancer. Due to the high number of target cells, however, side effects such as cytokine re...

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Detalles Bibliográficos
Autores principales: Klopp, Alexandre, Schreiber, Sophia, Kosinska, Anna D., Pulé, Martin, Protzer, Ulrike, Wisskirchen, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527178/
https://www.ncbi.nlm.nih.gov/pubmed/34691041
http://dx.doi.org/10.3389/fimmu.2021.734246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527178/
https://www.ncbi.nlm.nih.gov/pubmed/34691041
http://dx.doi.org/10.3389/fimmu.2021.734246

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