Insm1, Neurod1, and Pax6 promote murine pancreatic endocrine cell development through overlapping yet distinct RNA transcription and splicing programs

Insm1, Neurod1, and Pax6 are essential for the formation and function of pancreatic endocrine cells. Here, we report comparative immunohistochemical, transcriptomic, functional enrichment, and RNA splicing analyses of these genes using gene knock-out mice. Quantitative immunohistochemical analysis c...

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Detalles Bibliográficos
Autores principales: Dudek, Karrie D, Osipovich, Anna B, Cartailler, Jean-Philippe, Gu, Guoquing, Magnuson, Mark A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527475/
https://www.ncbi.nlm.nih.gov/pubmed/34534285
http://dx.doi.org/10.1093/g3journal/jkab303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527475/
https://www.ncbi.nlm.nih.gov/pubmed/34534285
http://dx.doi.org/10.1093/g3journal/jkab303

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