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Insm1, Neurod1, and Pax6 promote murine pancreatic endocrine cell development through overlapping yet distinct RNA transcription and splicing programs
Insm1, Neurod1, and Pax6 are essential for the formation and function of pancreatic endocrine cells. Here, we report comparative immunohistochemical, transcriptomic, functional enrichment, and RNA splicing analyses of these genes using gene knock-out mice. Quantitative immunohistochemical analysis c...
Autores principales: | Dudek, Karrie D, Osipovich, Anna B, Cartailler, Jean-Philippe, Gu, Guoquing, Magnuson, Mark A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527475/ https://www.ncbi.nlm.nih.gov/pubmed/34534285 http://dx.doi.org/10.1093/g3journal/jkab303 |
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