A Catecholaldehyde Metabolite of Norepinephrine Induces Myofibroblast Activation and Toxicity via the Receptor for Advanced Glycation Endproducts: Mitigating Role of l-Carnosine

[Image: see text] Monoamine oxidase (MAO) is rapidly gaining appreciation for its pathophysiologic role in cardiac injury and failure. Oxidative deamination of norepinephrine by MAO generates H(2)O(2) and the catecholaldehyde 3,4-dihydroxyphenylglycolaldehyde (DOPEGAL), the latter of which is a high...

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Detalles Bibliográficos
Autores principales: Monroe, T. Blake, Anderson, Ethan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527521/
https://www.ncbi.nlm.nih.gov/pubmed/34609854
http://dx.doi.org/10.1021/acs.chemrestox.1c00262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527521/
https://www.ncbi.nlm.nih.gov/pubmed/34609854
http://dx.doi.org/10.1021/acs.chemrestox.1c00262

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