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Characterization of Catecholaldehyde Adducts with Carnosine and l-Cysteine Reveals Their Potential as Biomarkers of Catecholaminergic Stress

[Image: see text] Monoamine oxidase (MAO) catalyzes the oxidative deamination of dopamine and norepinephrine to produce 3,4-dihydroxyphenylacetaldehyde (DOPAL) and 3,4-dihydroxyphenylglycolaldehyde (DOPEGAL), respectively. Both of these aldehydes are potently cytotoxic and have been implicated in pa...

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Detalles Bibliográficos
Autores principales: Crawford, Rachel A., Gilardoni, Ettore, Monroe, T. Blake, Regazzoni, Luca, Anderson, Ethan J., Doorn, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527522/
https://www.ncbi.nlm.nih.gov/pubmed/34506109
http://dx.doi.org/10.1021/acs.chemrestox.1c00153