Cargando…
Characterization of Catecholaldehyde Adducts with Carnosine and l-Cysteine Reveals Their Potential as Biomarkers of Catecholaminergic Stress
[Image: see text] Monoamine oxidase (MAO) catalyzes the oxidative deamination of dopamine and norepinephrine to produce 3,4-dihydroxyphenylacetaldehyde (DOPAL) and 3,4-dihydroxyphenylglycolaldehyde (DOPEGAL), respectively. Both of these aldehydes are potently cytotoxic and have been implicated in pa...
Autores principales: | Crawford, Rachel A., Gilardoni, Ettore, Monroe, T. Blake, Regazzoni, Luca, Anderson, Ethan J., Doorn, Jonathan A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527522/ https://www.ncbi.nlm.nih.gov/pubmed/34506109 http://dx.doi.org/10.1021/acs.chemrestox.1c00153 |
Ejemplares similares
-
A Catecholaldehyde
Metabolite of Norepinephrine Induces
Myofibroblast Activation and Toxicity via the Receptor for Advanced
Glycation Endproducts: Mitigating Role of l-Carnosine
por: Monroe, T. Blake, et al.
Publicado: (2021) -
The Catecholaldehyde Hypothesis for the Pathogenesis of Catecholaminergic Neurodegeneration: What We Know and What We Do Not Know
por: Goldstein, David S.
Publicado: (2021) -
The ergogenic effect of acute carnosine and anserine supplementation: dosing, timing, and underlying mechanism
por: de Jager, Sarah, et al.
Publicado: (2022) -
Benomyl, Aldehyde Dehydrogenase, DOPAL, and the Catecholaldehyde
Hypothesis for the Pathogenesis of Parkinson’s Disease
por: Casida, John E., et al.
Publicado: (2014) -
Exercise and β-alanine supplementation on carnosine-acrolein adduct in skeletal muscle
por: Carvalho, Victor H., et al.
Publicado: (2018)