Unusual course of disease and genetic profile in Li-Fraumeni syndrome-associated osteosarcoma – a case report

BACKGROUND: Osteosarcoma is a highly malignant tumour associated with numerous and complex genetic alterations like copy number alterations. Recent whole genome studies revealed distinct mutations in several candidate oncogenes. While clinical parameters stratify osteosarcoma patients in risk groups...

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Detalles Bibliográficos
Autores principales: Puzik, Alexander, Uhl, Markus, Ruf, Juri, Schumacher, Tilmann, Kontny, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527636/
https://www.ncbi.nlm.nih.gov/pubmed/34670578
http://dx.doi.org/10.1186/s13053-021-00202-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527636/
https://www.ncbi.nlm.nih.gov/pubmed/34670578
http://dx.doi.org/10.1186/s13053-021-00202-0

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