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Interaction between PSMD10 and GRP78 accelerates endoplasmic reticulum stress-mediated hepatic apoptosis induced by homocysteine

BACKGROUND: The liver plays an important role in production and metabolism of homocysteine (Hcy), which has been reported to be involved in liver injury. In our previous work, we confirm that Hcy can induce liver injury by activating endoplasmic reticulum (ER) stress. However, the underlying mechani...

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Detalles Bibliográficos
Autores principales: Xiao, Kun, Ma, Shengchao, Xu, Long, Ding, Ning, Zhang, Hui, Xie, Lin, Xu, Lingbo, Jiao, Yun, Zhang, Huiping, Jiang, Yideng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527788/
https://www.ncbi.nlm.nih.gov/pubmed/34666830
http://dx.doi.org/10.1186/s13099-021-00455-z