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Antisense noncoding mitochondrial RNA-2 gives rise to miR-4485-3p by Dicer processing in vitro

BACKGROUND: The antisense noncoding mitochondrial RNAs (ASncmtRNAs) derive from the mitochondrial 16S gene. Knockdown of these transcripts with chemically-modified antisense oligonucleotides induces proliferative arrest, apoptosis and invasiveness reduction in tumor but not normal cells. One of thes...

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Detalles Bibliográficos
Autores principales: Farfán, Nicole, Sanhueza, Nicole, Briones, Macarena, Burzio, Luis O., Burzio, Verónica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527801/
https://www.ncbi.nlm.nih.gov/pubmed/34666824
http://dx.doi.org/10.1186/s40659-021-00356-0