Cargando…
Antisense noncoding mitochondrial RNA-2 gives rise to miR-4485-3p by Dicer processing in vitro
BACKGROUND: The antisense noncoding mitochondrial RNAs (ASncmtRNAs) derive from the mitochondrial 16S gene. Knockdown of these transcripts with chemically-modified antisense oligonucleotides induces proliferative arrest, apoptosis and invasiveness reduction in tumor but not normal cells. One of thes...
Autores principales: | Farfán, Nicole, Sanhueza, Nicole, Briones, Macarena, Burzio, Luis O., Burzio, Verónica A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527801/ https://www.ncbi.nlm.nih.gov/pubmed/34666824 http://dx.doi.org/10.1186/s40659-021-00356-0 |
Ejemplares similares
-
HPV-18 E2 protein downregulates antisense noncoding mitochondrial RNA-2, delaying replicative senescence of human keratinocytes
por: Villota, Claudio, et al.
Publicado: (2018) -
Down-regulation of the Antisense Mitochondrial Non-coding RNAs (ncRNAs) Is a Unique Vulnerability of Cancer Cells and a Potential Target for Cancer Therapy
por: Vidaurre, Soledad, et al.
Publicado: (2014) -
Targeting antisense mitochondrial noncoding RNAs induces bladder cancer cell death and inhibition of tumor growth through reduction of survival and invasion factors
por: Borgna, Vincenzo, et al.
Publicado: (2020) -
Targeting antisense mitochondrial ncRNAs inhibits murine melanoma tumor growth and metastasis through reduction in survival and invasion factors
por: Lobos-González, Lorena, et al.
Publicado: (2016) -
Mitochondrial ncRNA targeting induces cell cycle arrest and tumor growth inhibition of MDA-MB-231 breast cancer cells through reduction of key cell cycle progression factors
por: Fitzpatrick, Christopher, et al.
Publicado: (2019)