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Safety and efficacy of a single intra-articular injection of a novel enhanced protein solution (JTA-004) compared to hylan G-F 20 in symptomatic knee osteoarthritis: a randomized, double-blind, controlled phase II/III study

BACKGROUND: New minimally invasive treatments are vital to delay joint replacement surgery in patients with knee osteoarthritis. This study was designed to select the most effective among three formulations of an enhanced protein solution containing clonidine, hyaluronic acid, and human plasma (JTA-...

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Detalles Bibliográficos
Autores principales: Bettonville, Marie, Léon, Marc, Margaux, Joëlle, Urbin-Choffray, Didier, Theunissen, Emilie, Besse-Hammer, Tatiana, Fortems, Yves, Verlinden, Séverine, Godeaux, Olivier, Delmarcelle, Anne-Sophie, Kaux, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527807/
https://www.ncbi.nlm.nih.gov/pubmed/34666767
http://dx.doi.org/10.1186/s12891-021-04750-3