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Safety and efficacy of a single intra-articular injection of a novel enhanced protein solution (JTA-004) compared to hylan G-F 20 in symptomatic knee osteoarthritis: a randomized, double-blind, controlled phase II/III study
BACKGROUND: New minimally invasive treatments are vital to delay joint replacement surgery in patients with knee osteoarthritis. This study was designed to select the most effective among three formulations of an enhanced protein solution containing clonidine, hyaluronic acid, and human plasma (JTA-...
Autores principales: | Bettonville, Marie, Léon, Marc, Margaux, Joëlle, Urbin-Choffray, Didier, Theunissen, Emilie, Besse-Hammer, Tatiana, Fortems, Yves, Verlinden, Séverine, Godeaux, Olivier, Delmarcelle, Anne-Sophie, Kaux, Jean-François |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527807/ https://www.ncbi.nlm.nih.gov/pubmed/34666767 http://dx.doi.org/10.1186/s12891-021-04750-3 |
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