Extending the Horizon of Homology Detection with Coevolution-based Structure Prediction

Traditional sequence analysis algorithms fail to identify distant homologies when they lie beyond a detection horizon. In this review, we discuss how co-evolution-based contact and distance prediction methods are pushing back this homology detection horizon, thereby yielding new functional insights...

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Detalles Bibliográficos
Autores principales: Sanchez-Pulido, Luis, Ponting, Chris P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527833/
https://www.ncbi.nlm.nih.gov/pubmed/34139218
http://dx.doi.org/10.1016/j.jmb.2021.167106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527833/
https://www.ncbi.nlm.nih.gov/pubmed/34139218
http://dx.doi.org/10.1016/j.jmb.2021.167106

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