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Cooperativity mediated by rationally selected combinations of human monoclonal antibodies targeting the henipavirus receptor binding protein

Hendra virus and Nipah virus (NiV), members of the Henipavirus (HNV) genus, are zoonotic paramyxoviruses known to cause severe disease across six mammalian orders, including humans. We isolated a panel of human monoclonal antibodies (mAbs) from the B cells of an individual with prior exposure to equ...

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Detalles Bibliográficos
Autores principales: Doyle, Michael P., Kose, Nurgun, Borisevich, Viktoriya, Binshtein, Elad, Amaya, Moushimi, Nagel, Marcus, Annand, Edward J., Armstrong, Erica, Bombardi, Robin, Dong, Jinhui, Schey, Kevin L., Broder, Christopher C., Zeitlin, Larry, Kuang, Erin A., Bornholdt, Zachary A., West, Brandyn R., Geisbert, Thomas W., Cross, Robert W., Crowe, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527959/
https://www.ncbi.nlm.nih.gov/pubmed/34469726
http://dx.doi.org/10.1016/j.celrep.2021.109628