Impact of Sickle Cell Trait Hemoglobin on the Intraerythrocytic Transcriptional Program of Plasmodium falciparum

Sickle-trait hemoglobin (HbAS) confers nearly complete protection from severe, life-threatening falciparum malaria in African children. Despite this clear protection, the molecular mechanisms by which HbAS confers these protective phenotypes remain incompletely understood. As a forward genetic scree...

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Detalles Bibliográficos
Autores principales: Saelens, Joseph W., Petersen, Jens E. V., Freedman, Elizabeth, Moseley, Robert C., Konaté, Drissa, Diakité, Seidina A. S., Traoré, Karim, Vance, Natalie, Fairhurst, Rick M., Diakité, Mahamadou, Haase, Steven B., Taylor, Steve M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527989/
https://www.ncbi.nlm.nih.gov/pubmed/34668757
http://dx.doi.org/10.1128/mSphere.00755-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527989/
https://www.ncbi.nlm.nih.gov/pubmed/34668757
http://dx.doi.org/10.1128/mSphere.00755-21

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