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Impact of Sickle Cell Trait Hemoglobin on the Intraerythrocytic Transcriptional Program of Plasmodium falciparum
Sickle-trait hemoglobin (HbAS) confers nearly complete protection from severe, life-threatening falciparum malaria in African children. Despite this clear protection, the molecular mechanisms by which HbAS confers these protective phenotypes remain incompletely understood. As a forward genetic scree...
Autores principales: | Saelens, Joseph W., Petersen, Jens E. V., Freedman, Elizabeth, Moseley, Robert C., Konaté, Drissa, Diakité, Seidina A. S., Traoré, Karim, Vance, Natalie, Fairhurst, Rick M., Diakité, Mahamadou, Haase, Steven B., Taylor, Steve M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8527989/ https://www.ncbi.nlm.nih.gov/pubmed/34668757 http://dx.doi.org/10.1128/mSphere.00755-21 |
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