Targeted protein oxidation using a chromophore-modified rapamycin analog

Chemically induced dimerization of FKBP and FRB using rapamycin and rapamycin analogs has been utilized in a variety of biological applications. Formation of the FKBP-rapamycin-FRB ternary complex is typically used to activate a biological process and this interaction has proven to be essentially ir...

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Detalles Bibliográficos
Autores principales: Courtney, Taylor M., Hankinson, Chasity P., Horst, Trevor J., Deiters, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528027/
https://www.ncbi.nlm.nih.gov/pubmed/34777761
http://dx.doi.org/10.1039/d1sc04464h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528027/
https://www.ncbi.nlm.nih.gov/pubmed/34777761
http://dx.doi.org/10.1039/d1sc04464h

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