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Genetically-targeted photorelease of endocannabinoids enables optical control of GPR55 in pancreatic β-cells

Fatty acid amides (FAAs) are a family of second-messenger lipids that target cannabinoid receptors, and are known mediators of glucose-stimulated insulin secretion from pancreatic β-cells. Due to the diversity observed in FAA structure and pharmacology, coupled with the expression of at least 3 diff...

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Detalles Bibliográficos
Autores principales: Tobias, Janelle M., Rajic, Gabriela, Viray, Alexander E. G., Icka-Araki, David, Frank, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528030/
https://www.ncbi.nlm.nih.gov/pubmed/34777770
http://dx.doi.org/10.1039/d1sc02527a