Cargando…

Peptoid-based reprogrammable template for cell-permeable inhibitors of protein–protein interactions

The development of inhibitors of intracellular protein–protein interactions (PPIs) is of great significance for drug discovery, but the generation of a cell-permeable molecule with high affinity to protein is challenging. Oligo(N-substituted glycines) (oligo-NSGs), referred to as peptoids, are attra...

Descripción completa

Detalles Bibliográficos
Autores principales: Fukuda, Yasuhiro, Yokomine, Marin, Kuroda, Daisuke, Tsumoto, Kouhei, Morimoto, Jumpei, Sando, Shinsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528041/
https://www.ncbi.nlm.nih.gov/pubmed/34777747
http://dx.doi.org/10.1039/d1sc01560e