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Chemoselective cysteine or disulfide modification via single atom substitution in chloromethyl acryl reagents
The development of bioconjugation chemistry has enabled the combination of various synthetic functionalities to proteins, giving rise to new classes of protein conjugates with functions well beyond what Nature can provide. Despite the progress in bioconjugation chemistry, there are no reagents devel...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528048/ https://www.ncbi.nlm.nih.gov/pubmed/34777751 http://dx.doi.org/10.1039/d1sc03250j |