Repurposing of the Tamoxifen Metabolites to Treat Methicillin-Resistant Staphylococcus epidermidis and Vancomycin-Resistant Enterococcus faecalis Infections

Repurposing drugs provides a new approach to the fight against multidrug-resistant (MDR) bacteria. We have reported that three major tamoxifen metabolites, N-desmethyltamoxifen (DTAM), 4-hydroxytamoxifen (HTAM), and endoxifen (ENDX), presented bactericidal activity against Acinetobacter baumannii an...

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Detalles Bibliográficos
Autores principales: Miró-Canturri, Andrea, Vila-Domínguez, Andrea, Caretero-Ledesma, Marta, Ayerbe-Algaba, Rafael, Pachón, Jerónimo, Jiménez-Mejías, Manuel Enrique, Smani, Younes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528103/
https://www.ncbi.nlm.nih.gov/pubmed/34668743
http://dx.doi.org/10.1128/Spectrum.00403-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528103/
https://www.ncbi.nlm.nih.gov/pubmed/34668743
http://dx.doi.org/10.1128/Spectrum.00403-21

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