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CODEHOP-Mediated PCR Improves HIV-1 Genotyping and Detection of Variants by MinION Sequencing

HIV-1 is genetically heterogeneous, having different subtypes and circulating recombinant forms (CRFs). HIV-1 genotyping is used to determine drug resistance profiles and is based on the use of a mixture of consensus and degenerate primers targeting the pol gene. However, the use of this type of pri...

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Detalles Bibliográficos
Autores principales: Sarkhouh, Horeyah, Chehadeh, Wassim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528109/
https://www.ncbi.nlm.nih.gov/pubmed/34668751
http://dx.doi.org/10.1128/Spectrum.01432-21