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Network-Based Approaches Reveal Potential Therapeutic Targets for Host-Directed Antileishmanial Therapy Driving Drug Repurposing

Leishmania parasites are the causal agent of leishmaniasis, an endemic disease in more than 90 countries worldwide. Over the years, traditional approaches focused on the parasite when developing treatments against leishmaniasis. Despite numerous attempts, there is not yet a universal treatment, and...

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Detalles Bibliográficos
Autores principales: Martinez-Hernandez, J. Eduardo, Hammoud, Zaynab, de Sousa, Alessandra Mara, Kramer, Frank, do Monte-Neto, Rubens L., Maracaja-Coutinho, Vinicius, Martin, Alberto J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528132/
https://www.ncbi.nlm.nih.gov/pubmed/34668739
http://dx.doi.org/10.1128/Spectrum.01018-21