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Safety of Lubiprostone in Pediatric Patients With Functional Constipation: A Nonrandomized, Open-Label Trial

OBJECTIVES: Pediatric functional constipation (PFC) affects up to 30% of children. Current treatments often do not sustain symptomatic relief. Lubiprostone is a locally acting chloride channel activator that promotes fluid secretion into the small bowel without affecting serum electrolyte concentrat...

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Detalles Bibliográficos
Autores principales: Hussain, Sunny Z., Labrum, Barrett, Mareya, Shadreck, Stripling, Stephen, Clifford, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528133/
https://www.ncbi.nlm.nih.gov/pubmed/34387619
http://dx.doi.org/10.1097/MPG.0000000000003280