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Classical and Non-classical Fibrosis Phenotypes Are Revealed by Lung and Cardiac Like Microvascular Tissues On-Chip

Fibrosis, a hallmark of many cardiac and pulmonary diseases, is characterized by excess deposition of extracellular matrix proteins and increased tissue stiffness. This serious pathologic condition is thought to stem majorly from local stromal cell activation. Most studies have focused on the role o...

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Detalles Bibliográficos
Autores principales: Akinbote, Akinola, Beltran-Sastre, Violeta, Cherubini, Marta, Visone, Roberta, Hajal, Cynthia, Cobanoglu, Defne, Haase, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528192/
https://www.ncbi.nlm.nih.gov/pubmed/34690810
http://dx.doi.org/10.3389/fphys.2021.735915