Vitamin D levels do not cause vitamin-drug interactions with dexamethasone or dasatinib in mice

Vitamin D(3) (VD(3)) induces intestinal CYP3A that metabolizes orally administered anti-leukemic chemotherapeutic substrates dexamethasone (DEX) and dasatinib potentially causing a vitamin-drug interaction. To determine the impact of VD(3) status on systemic exposure and efficacy of these chemothera...

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Detalles Bibliográficos
Autores principales: Annu, Kavya, Yasuda, Kazuto, Caufield, William V., Freeman, Burgess B., Schuetz, Erin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528301/
https://www.ncbi.nlm.nih.gov/pubmed/34669728
http://dx.doi.org/10.1371/journal.pone.0258579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528301/
https://www.ncbi.nlm.nih.gov/pubmed/34669728
http://dx.doi.org/10.1371/journal.pone.0258579

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