Cargando…
Vitamin D levels do not cause vitamin-drug interactions with dexamethasone or dasatinib in mice
Vitamin D(3) (VD(3)) induces intestinal CYP3A that metabolizes orally administered anti-leukemic chemotherapeutic substrates dexamethasone (DEX) and dasatinib potentially causing a vitamin-drug interaction. To determine the impact of VD(3) status on systemic exposure and efficacy of these chemothera...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528301/ https://www.ncbi.nlm.nih.gov/pubmed/34669728 http://dx.doi.org/10.1371/journal.pone.0258579 |