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PINK1 antagonize intracerebral hemorrhage by promoting mitochondrial autophagy

BACKGROUND: Intracerebral hemorrhage (ICH) causes neurotransmitter release, oligemia, membrane depolarization, mitochondrial dysfunction, and results in the high rate of mortality and functional disability. Here, we focus on PTEN‐induced kinase 1 (PINK1), a mitochondrial‐targeted protein kinase, and...

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Detalles Bibliográficos
Autores principales: Li, Jingchen, Wu, Xiaoyun, He, Yanbo, Wu, Song, Guo, Erkun, Feng, Yan, Yang, Jipeng, Li, Jianliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528457/
https://www.ncbi.nlm.nih.gov/pubmed/34453779
http://dx.doi.org/10.1002/acn3.51425