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mTOR signaling mediates ILC3-driven immunopathology

Innate lymphoid cells (ILCs) have a protective immune function at mucosal tissues but can also contribute to immunopathology. Previous work has shown that the serine/threonine kinase mammalian target of rapamycin complex 1 (mTORC1) is involved in generating protective ILC3 cytokine responses during...

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Detalles Bibliográficos
Autores principales: Teufel, Claudia, Horvath, Edit, Peter, Annick, Ercan, Caner, Piscuoglio, Salvatore, Hall, Michael N., Finke, Daniela, Lehmann, Frank M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528695/
https://www.ncbi.nlm.nih.gov/pubmed/34341503
http://dx.doi.org/10.1038/s41385-021-00432-4