Non-hematopoietic IL-4Rα expression contributes to fructose-driven obesity and metabolic sequelae

OBJECTIVE: The risks of excess sugar intake in addition to high-fat diet consumption on immunopathogenesis of obesity-associated metabolic diseases are poorly defined. Interleukin-4 (IL-4) and IL-13 signaling via IL-4Rα regulates adipose tissue lipolysis, insulin sensitivity, and liver fibrosis in o...

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Detalles Bibliográficos
Autores principales: Damen, Michelle S. M. A., Stankiewicz, Traci E., Park, Se-Hyung, Helsley, Robert N., Chan, Calvin C., Moreno-Fernandez, Maria E., Doll, Jessica R., Szabo, Sara, Herbert, De’Broski R., Softic, Samir, Divanovic, Senad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528699/
https://www.ncbi.nlm.nih.gov/pubmed/34302121
http://dx.doi.org/10.1038/s41366-021-00902-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528699/
https://www.ncbi.nlm.nih.gov/pubmed/34302121
http://dx.doi.org/10.1038/s41366-021-00902-6

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