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Tissue signals imprint Aiolos expression in ILC2s to modulate type 2 immunity

Group 2 innate lymphoid cells (ILC2s) manifest tissue heterogeneity and are crucial modulators of regional immune responses. The molecular mechanisms regulating tissue ILC2 properties remain elusive. Here, we interrogate the signatures of ILC2s from five tissues at the transcriptome and epigenetic l...

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Detalles Bibliográficos
Autores principales: Qiu, Jinxin, Zhang, Jingjing, Ji, Yan, Sun, Hanxiao, Gu, Zhitao, Sun, Qiangling, Bai, Meizhu, Gong, Jue, Tang, Jupei, Zhang, Yunpeng, Li, Shiyang, Shao, Zhen, Li, Jinsong, Sheng, Huiming, Shen, Lei, Qiu, Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528704/
https://www.ncbi.nlm.nih.gov/pubmed/34349237
http://dx.doi.org/10.1038/s41385-021-00431-5