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PRKAR2A deficiency protects mice from experimental colitis by increasing IFN-stimulated gene expression and modulating the intestinal microbiota

Protein kinase A (PKA) plays an important role in regulating inflammation via its catalytic subunits. Recently, PKA regulatory subunits have been reported to directly modulate some signaling pathways and alleviate inflammation. However, the role of PKA regulatory subunits in colonic inflammation rem...

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Detalles Bibliográficos
Autores principales: Wei, Lumin, Zhang, Rongjing, Zhang, Jinzhao, Li, Juanjuan, Kong, Deping, Wang, Qi, Fang, Jing, Wang, Lifu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528707/
https://www.ncbi.nlm.nih.gov/pubmed/34349238
http://dx.doi.org/10.1038/s41385-021-00426-2