Cargando…
PRKAR2A deficiency protects mice from experimental colitis by increasing IFN-stimulated gene expression and modulating the intestinal microbiota
Protein kinase A (PKA) plays an important role in regulating inflammation via its catalytic subunits. Recently, PKA regulatory subunits have been reported to directly modulate some signaling pathways and alleviate inflammation. However, the role of PKA regulatory subunits in colonic inflammation rem...
Autores principales: | Wei, Lumin, Zhang, Rongjing, Zhang, Jinzhao, Li, Juanjuan, Kong, Deping, Wang, Qi, Fang, Jing, Wang, Lifu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528707/ https://www.ncbi.nlm.nih.gov/pubmed/34349238 http://dx.doi.org/10.1038/s41385-021-00426-2 |
Ejemplares similares
-
Hematopoietic neoplasms in Prkar2a-deficient mice
por: Saloustros, Emmanouil, et al.
Publicado: (2015) -
Intestinal Claudin-7 deficiency impacts the intestinal microbiota in mice with colitis
por: Ding, Yuhan, et al.
Publicado: (2022) -
PRKAR1A deficiency impedes hypertrophy and reduces heart size
por: Liu, Yuening, et al.
Publicado: (2020) -
PRKAR2A‐derived circular RNAs promote the malignant transformation of colitis and distinguish patients with colitis‐associated colorectal cancer
por: Wan, Daiwei, et al.
Publicado: (2022) -
SUN-235 Deficient Fear Extinction in PRKAR1A-Defective Mice
por: Keil, Margaret, et al.
Publicado: (2020)