Cytokine exposure mediates transcriptional activation of the orphan nuclear receptor Nur77 in hematopoietic cells

The orphan nuclear receptor Nur77 is an immediate-early response gene that based on tissue and cell context is implicated in a plethora of cellular processes, including proliferation, differentiation, apoptosis, metabolism, and inflammation. Nur77 has a ligand-binding pocket that is obstructed by hy...

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Detalles Bibliográficos
Autores principales: di Martino, Orsola, Niu, Haixia, Hadwiger, Gayla, Ferris, Margaret A., Welch, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528724/
https://www.ncbi.nlm.nih.gov/pubmed/34571009
http://dx.doi.org/10.1016/j.jbc.2021.101240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528724/
https://www.ncbi.nlm.nih.gov/pubmed/34571009
http://dx.doi.org/10.1016/j.jbc.2021.101240

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