Design and synthesis of heterocyclic azole based bioactive compounds: Molecular structures, quantum simulation, and mechanistic studies through docking as multi-target inhibitors of SARS-CoV-2 and cytotoxicity

Two heterocyclic azole compounds, 3-(2,3-dihydrobenzo[d]thiazol-2-yl)-4H-chromen-4-one (SVS1) and 5-(1H-indol-3-yl)-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (SVS2) were obtained unexpectedly from 2-aminothiophenol and 4-oxo-4H-chromene-3-carbaldehyde (for SVS1), and (E)-2-((1H-indol-3-yl)meth...

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Detalles Bibliográficos
Autores principales: Haribabu, Jebiti, Garisetti, Vasavi, Malekshah, Rahime Eshaghi, Srividya, Swaminathan, Gayathri, Dasararaju, Bhuvanesh, Nattamai, Mangalaraja, Ramalinga Viswanathan, Echeverria, Cesar, Karvembu, Ramasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528790/
https://www.ncbi.nlm.nih.gov/pubmed/34697505
http://dx.doi.org/10.1016/j.molstruc.2021.131782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528790/
https://www.ncbi.nlm.nih.gov/pubmed/34697505
http://dx.doi.org/10.1016/j.molstruc.2021.131782

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