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Structure of the human RNA polymerase I elongation complex

Eukaryotic RNA polymerase I (Pol I) transcribes ribosomal DNA and generates RNA for ribosome synthesis. Pol I accounts for the majority of cellular transcription activity and dysregulation of Pol I transcription leads to cancers and ribosomopathies. Despite extensive structural studies of yeast Pol...

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Detalles Bibliográficos
Autores principales: Zhao, Dan, Liu, Weida, Chen, Ke, Wu, Zihan, Yang, Huirong, Xu, Yanhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528822/
https://www.ncbi.nlm.nih.gov/pubmed/34671025
http://dx.doi.org/10.1038/s41421-021-00335-5