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Structure of the human RNA polymerase I elongation complex

Eukaryotic RNA polymerase I (Pol I) transcribes ribosomal DNA and generates RNA for ribosome synthesis. Pol I accounts for the majority of cellular transcription activity and dysregulation of Pol I transcription leads to cancers and ribosomopathies. Despite extensive structural studies of yeast Pol...

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Detalles Bibliográficos
Autores principales:	Zhao, Dan, Liu, Weida, Chen, Ke, Wu, Zihan, Yang, Huirong, Xu, Yanhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Singapore 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528822/ https://www.ncbi.nlm.nih.gov/pubmed/34671025 http://dx.doi.org/10.1038/s41421-021-00335-5

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