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Novel strain-level resolution of Crohn’s disease mucosa-associated microbiota via an ex vivo combination of microbe culture and metagenomic sequencing

The mucosa-associated microbiota is widely recognized as a potential trigger for Crohn’s disease pathophysiology but remains largely uncharacterised beyond its taxonomic composition. Unlike stool microbiota, the functional characterisation of these communities using current DNA/RNA sequencing approa...

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Detalles Bibliográficos
Autores principales: Teh, J. J., Berendsen, E. M., Hoedt, E. C., Kang, S., Zhang, J., Zhang, F., Liu, Q., Hamilton, A. L., Wilson-O’Brien, A., Ching, J., Sung, J. J. Y., Yu, J., Ng, S. C., Kamm, M. A., Morrison, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528831/
https://www.ncbi.nlm.nih.gov/pubmed/34035441
http://dx.doi.org/10.1038/s41396-021-00991-1