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Identification of histone methyltransferase NSD2 as an important oncogenic gene in colorectal cancer

Colorectal cancer (CRC) is the second common cause of cancer-related human mortalities. Dysregulation of histone 3 (H3) methylation could lead to transcriptional activation of multiple oncogenes, which is closely associated with CRC tumorigenesis and progression. Nuclear receptor-binding SET Domain...

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Detalles Bibliográficos
Autores principales: Zhao, Li-hao, Li, Quan, Huang, Zhi-Jun, Sun, Mi-Xue, Lu, Jing-jing, Zhang, Xiao-hua, Li, Gang, Wu, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528846/
https://www.ncbi.nlm.nih.gov/pubmed/34671018
http://dx.doi.org/10.1038/s41419-021-04267-6