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B7–H3 regulates osteoclast differentiation via type I interferon-dependent IDO induction

While their function, as immune checkpoint molecules, is well known, B7-family proteins also function as regulatory molecules in bone remodeling. B7–H3 is a receptor ligand of the B7 family that functions primarily as a negative immune checkpoint. While the regulatory function of B7–H3 in osteoblast...

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Detalles Bibliográficos
Autores principales: Oh, Younseo, Park, Robin, Kim, So Yeon, Park, Sung-ho, Jo, Sungsin, Kim, Tae-Hwan, Ji, Jong Dae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528854/
https://www.ncbi.nlm.nih.gov/pubmed/34671026
http://dx.doi.org/10.1038/s41419-021-04275-6