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Dynamic FRET-FLIM based screening of signal transduction pathways

Fluorescence Lifetime Imaging (FLIM) is an intrinsically quantitative method to screen for protein–protein interactions and is frequently used to record the outcome of signal transduction events. With new highly sensitive and photon efficient FLIM instrumentation, the technique also becomes attracti...

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Detalles Bibliográficos
Autores principales: Harkes, Rolf, Kukk, Olga, Mukherjee, Sravasti, Klarenbeek, Jeffrey, van den Broek, Bram, Jalink, Kees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528867/
https://www.ncbi.nlm.nih.gov/pubmed/34671065
http://dx.doi.org/10.1038/s41598-021-00098-9